A Cure for Amine Allergies?

Amine allergy swollen knee joints

Amine allergy swollen knee joints? These are my knees today. I've been bingeing on high amine foods for four days now. They are not swollen and do not hurt. They're a bit stiff. But they should be totally exploded from my amine allergy.

I just found something that may or may not help you. It has certainly helped me.

Correct me if I am misstating any of this information…

Apparently with some forms of amine allergies, it can cause an absorption problem in the body – particularly with Zinc and B-Vitamins. The lack of these vitamins causes a more severe reaction to amines. It seems to be a nasty cycle of making things worse.

  • Real Failsafe Meals blogger’s daughter has, “food intolerances (to salicylates and amines), and found they are caused by a condition called Pyroluria. In very basic terms, pyroles (a by-product of haemoglobin production) grab hold of B6 and Zinc and take them out of the body via the urine. This leads to massive deficiencies of zinc and B6… and on the opposite end of the scale, toxic levels of copper (copper and zinc work against each other). Check the FAQs documents [of this Facebook page for Pyroluria information].”

Upon reading several key forums, experiences, and blogs, I decided to use myself as a Guinea pig. I have been taking Zinc (zinc and calcium, mixed) and B-Vitamins for three weeks now, daily. I am only taking one per day of both the Super B-Complex and the Zinc/Calcium blend. They are meant as daily multi-vitamins, so I do not have much fear of overdoing it.

WARNING: More then 50 MG of Zinc can be lethal. See your doctor before taking over 50MG of Zinc (thanks for the heads up, Allergic Vegetarian!).

In Nature Made Zinc/Calcium Tablets:

  • Vitamin D3: 200 I.U. (50% Daily Value)
  • Calcium 333 mg (33% Daily Value)
  • Magnesium 133 mg (33% Daily Value)
  • Zinc 5 mg (33% Daily Value)
In Nature Made Super B-Complex Tablets:
  • Vitamin C 150 mg (250% Daily Value)
  • Thiamin 100 mg (6667% Daily Value)
  • Riboflavin 20 mg (1176% Daily Value)
  • Niacin 25 mg (125% Daily Value)
  • Vitamin B6 2mg (100% Daily Value)
  • Folic Acid 400 mcg (100% Daily Value)
  • Vitamin B12 15 mcg (250% Daily Value)
  • Biotin 30 mcg (10% Daily Value)
  • Pantothenic Acid 5.5 mg (55% Daily Value)

For the last four days, I have been in the moderate amines, eating things like Mexican rice (cooked with tomato paste), hot sauces, avocado, catsup, soy sauce, wild mushroom ragout, miso soup, a couple fingers of scotch, and an entire jar of marinara.

The last time I ate a bowl of marinara and pasta, I was so exploded that by the time I finished eating, my amine allergy had already caused my knee to swell. Within an hour, I could barely walk. Stairs were impossible.

This time, I’ve been eating amines all over, and though my joints are a little stiff, that’s all they are. Just a little stiff. I am positively amazed. I know there are tests you can take to measure your zinc or B-vitamin levels, and perhaps that is what I’ll do next. But while I’m onto this hunch, I feel it necessary to pass this gem along to you. I don’t know if it will work for you, but it’s certainly worth trying. Good luck, and let me know your results if you try it!

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7 CommentsLeave a comment

  1. Well…. that is VERY INTERESTING!! We have just recently discovered that my daughter’s food intolerances (to salicylates and amines) are caused by a condition called Pyroluria. In very basic terms, pyroles (a by-product of haemoglobin production) grab hold of B6 and Zinc and take them out of the body via the urine. This leads to massive deficiencies of zinc and B6… and on the opposite end of the scale, toxic levels of copper. (copper and zinc work against each other) You will find this facebook page most interesting, I am sure: http://www.facebook.com/groups/114586101398/#!/groups/114586101398/ Check the FAQs documents.

    • Thank you for that info! I am going to see if I can find a doctor in the US to help me get my levels tested so that I can take the proper amount. What I’m wondering is whether there are other natural drugs/herbs/vitamins/oils that I can take that will balance out whatever is causing this imbalance and allergy to begin with. Do you have any experience in this, or know of any doctors in the US that can do a workup for me for zinc, B-vitamins, copper, etc.?

      • If you go to that Pyroluria page, they’ll be able to direct you. I’m in Australia. You need a doctor specially trained in this field. Most GPs won’t know much about it. I’m relatively new to this, so I don’t want to go guessing at names I *Think* I know. 🙂 Really… go to the facebook page where there are Americans who will know or sure. Good luck!

  2. WARNING: More then 50 MG of Zinc can be lethal.
    See your doctor before taking over 50MG of Zinc.

    Celiac disease (gluten allergy) does rob your body of vitamins and minerals because it burrows holes on your intestine. This leads me to wonder, if an Amine allergy can have similiar effects? I did find that the lower intestine deals with vitamin absorption, so if this is damaged, then malabsorption issues may be had. However, I failed at finding any site addressing this issue.

    Also, I found out that alcohol (including vinegar, as it contains alcohol) can damage the lower intestine. I don’t know how much is needed to cause damage but maybe alcohol intolerance may have a negative effect on amine processing, and be related to having an amine allergy? Not sure.

    Concerning Amines… might be useful to some people.
    Quote from http://www.dietitian.com/allergie.html (Joanne Larsen, MS RD LD)
    An amine is derived from an amino acids which can be found in every food with protein. Even fruit has some protein. Some internally produced amines are thyroxine (hormone secreted by the thyroid gland which regulates the metabolism), epinephrine (same as adrenalin – hormone which causes blood vessels to constrict and is secreted by the adrenal glands which sit on top of the kidneys), norepinephrine (maintains blood pressure during shock) and melatonin (hormone secreted by pineal gland in the brain which induces sleep. Melatonin is derived from serotonin (regulates sleep, appetite, mood, pain and causes blood vessels to narrow). BTW, amines need a nutrient called pantothenic acid to be metabolized. Pantothenic acid is found in chicken, beef, potatoes, oats, cereals, tomato products, liver, kidney, yeast, egg yolk, broccoli and whole grains.

    • Thanks for this great information! I And an interesting hypothesis about the amine/gluten and damage to the intestines. Do you suppose it is a bit like “leaky gut syndrome” then?

      Also, how ironic that amines require foods high in amines (for the vast majority) in order to process out of the body.

  3. […] A Cure for Amine Allergies? […]

  4. Great! We ve been battling selfdiagnosed amine intolerance for a year…. Maybe a light


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